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Image Search Results
Journal: Experimental Hematology & Oncology
Article Title: Preclinical investigations and a first-in-human phase 1a trial of JS007, a novel anti-CTLA-4 antibody, in patients with advanced solid tumors
doi: 10.1186/s40164-024-00567-7
Figure Lengend Snippet: JS007 binding affinity to CTLA-4 protein and Fc receptor by Biacore
Article Snippet: The affinity of JS007 for Fc receptors was determined using Biacore (GE Healthcare Life Sciences), in which anti-His tag antibody was coupled to a CM5 chip surface, followed by capturing the His-tagged recombinant human FcγRIIIa (CD16a) V176 (Junmeng Biomedical, 20200421), FcγRIIIa (CD16a) F176 (Junmeng Biomedical, 20200421),
Techniques: Binding Assay, Recombinant